The Seahawks suffered their second devasting loss in the Bay Area, losing to the San Francisco 49ers 40-21. Their first was the "chamber of horrors" that awaited the 'Hawks in a 33-3 loss on Halloween to the Oakland Raiders. A "garbage time" Seahawk touchdown was costly as Deon Butler broke his leg on the play. The Seahawks were already without Mike Williams and Ben Obomanu. Leon Washington scored on a 93 yard kick-off return for the Seahawks.